What are protein domains?
A protein domain is a unit within a protein that has a distinct functional or structural role in a protein. These are made of amino acid residues. Proteins can be made up of multiple domains [1]. Protein domains can be identified using FASTA data along with a database such as SMART or Interpro. After searching with your FASTA sequence, these websites give results showing what domains are in your protein.
References
[1] Embl-Ebi. (n.d.). What are protein domains?. Protein classification. https://www.ebi.ac.uk/training/online/courses/protein-classification-intro-ebi-resources/protein-classification/what-are-protein-domains/
[2] Barbieri, R., Bertelli, S., Pusch, M., & Gavazzo, P. (2019). Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene. The Journal of Headache and Pain, 20(1). https://doi.org/10.1186/s10194-019-1056-2
Images created in BioRender
[2] Barbieri, R., Bertelli, S., Pusch, M., & Gavazzo, P. (2019). Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene. The Journal of Headache and Pain, 20(1). https://doi.org/10.1186/s10194-019-1056-2
Images created in BioRender
About the website
This web page was produced as an assignment for Genetics 564, an undergraduate capstone course at UW-Madison
Joely Swanson, [email protected]
Last updated April 9th, 2024
Genetics 564 website
Joely Swanson, [email protected]
Last updated April 9th, 2024
Genetics 564 website